ubet63 casino register philippines
777 fishing slot
777 fishing slot
Jimmy Carter, 39th US president, Nobel winner, dies at 100Unlike scores of people who scrambled for the blockbuster drugs Ozempic and Wegovy to lose weight in recent years, Danielle Griffin had no trouble getting them. The 38-year-old information technology worker from New Mexico had a prescription. Her pharmacy had the drugs in stock. And her health insurance covered all but $25 to $50 of the monthly cost. For Griffin, the hardest part of using the new drugs wasn’t access. It was finding out that the much-hyped medications didn’t really work for her. “I have been on Wegovy for a year and a half and have only lost 13 pounds,” said Griffin, who watches her diet, drinks plenty of water and exercises regularly. “I’ve done everything right with no success. It’s discouraging.” In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight — up to 50 pounds or more in many cases. But roughly 10% to 15% of patients in those trials were “nonresponders” who lost less than 5% of their body weight. Now that millions of people have used the drugs, several obesity experts told The Associated Press that perhaps 20% of patients — as many as 1 in 5 — may not respond well to the medications. It's a little-known consequence of the obesity drug boom, according to doctors who caution eager patients not to expect one-size-fits-all results. “It's all about explaining that different people have different responses,” said Dr. Fatima Cody Stanford, an obesity expert at Massachusetts General Hospital The drugs are known as GLP-1 receptor agonists because they mimic a hormone in the body known as glucagon-like peptide 1. Genetics, hormones and variability in how the brain regulates energy can all influence weight — and a person's response to the drugs, Stanford said. Medical conditions such as sleep apnea can prevent weight loss, as can certain common medications, such as antidepressants, steroids and contraceptives. “This is a disease that stems from the brain,” said Stanford. “The dysfunction may not be the same” from patient to patient. Despite such cautions, patients are often upset when they start getting the weekly injections but the numbers on the scale barely budge. “It can be devastating,” said Dr. Katherine Saunders, an obesity expert at Weill Cornell Medicine and co-founder of the obesity treatment company FlyteHealth. “With such high expectations, there’s so much room for disappointment.” That was the case for Griffin, who has battled obesity since childhood and hoped to shed 70 pounds using Wegovy. The drug helped reduce her appetite and lowered her risk of diabetes, but she saw little change in weight. “It’s an emotional roller coaster,” she said. “You want it to work like it does for everybody else.” The medications are typically prescribed along with eating behavior and lifestyle changes. It’s usually clear within weeks whether someone will respond to the drugs, said Dr. Jody Dushay, an endocrine specialist at Beth Israel Deaconess Medical Center. Weight loss typically begins right away and continues as the dosage increases. For some patients, that just doesn't happen. For others, side effects such as nausea, vomiting and diarrhea force them to halt the medications, Dushay said. In such situations, patients who were counting on the new drugs to pare pounds may think they’re out of options. “I tell them: It's not game over,” Dushay said. Trying a different version of the new class of drugs may help. Griffin, who didn't respond well to Wegovy, has started using Zepbound, which targets an additional hormone pathway in the body. After three months of using the drug, she has lost 7 pounds. “I'm hoping it's slow and steady,” she said. Other people respond well to older drugs, the experts said. Changing diet, exercise, sleep and stress habits can also have profound effects. Figuring out what works typically requires a doctor trained to treat obesity, Saunders noted. “Obesity is such a complex disease that really needs to be treated very comprehensively,” she said. “If what we’re prescribing doesn’t work, we always have a backup plan.” The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
The implementation of heightened security measures at Guangzhou Metro stations has understandably raised questions and concerns among passengers. Many have wondered whether these measures are temporary responses to recent events or if they will become permanent fixtures within the subway system. In response to these queries, Guangzhou Metro customer service has emphasized that the security measures are a part of the metro's commitment to ensuring a safe and secure environment for all passengers on a routine basis.In conclusion, the bond between Diawara and Umpire B. Fee, as well as the understanding that Coach Amorim brings as a former player, highlight the importance of mutual respect and empathy in sports. These relationships remind us that beyond the goals and victories, it is the connections and shared experiences that truly make the game of soccer a beautiful and enriching journey for all involved.ROCHESTER, N.Y. — The holiday shopping season unofficially kicks off in just a couple of days on what’s known as Black Friday. What are the trends and are folks expected to fork over the funds for the presents this year? A local mall general manager and shoppers give their take. “We obviously love this time of year," said the General Manager of Ontario County’s Eastview Mall Mike Kauffman. "[It's a] great time of year for us. Our merchants love it. We're expecting a really good holiday season for us.” Kauffman says stores in the Victor mall are gearing up for a huge weekend of sales. “This is obviously a huge weekend for us," he said. "It's kind of a symbolic start to the season. It’s been a good year. And normally when we have a good year, January through October, it carries on through the holidays.” Kauffman says the trends show that people are returning to shopping in person. “They like to come out and kind of see and feel and touch the products they want to buy," he said. "But they also like to get out and see their friends and come out to the mall with their family and have a good time.” What are folks buying this year? Kauffman says electronics and clothes. “It's more electronic than anything else," shopper Zavid Butman said. "Like, just with how stuff is nowadays, it's mostly just like clothes and shoes and stuff like that, because it's more stuff that people need. Because money's real tight with a lot of people." “Well, [I'm shopping] mostly for my grandchildren," said shopper Mary Habasi. "So it's like Minecraft and Zelda and Legos. What else do they like? Pretty much, they like anything." "]I'm shopping for] pretty much anything sentimental," shopper Ally Rauber said. "I like getting people things that they're going to hold on to for a while. Anything that involves family members or loved ones that is going to hold them close.” But Kauffman says the gift-giving trend seems to be shifting toward more social experience gifts – like tickets to events or gift cards to restaurants, “I think we're going to see that category probably amongst the strongest categories for us this season," he said. “My wife and I have agreed since we've been getting my niece and nephew gifts that we're going to get them one small gift every year for the last four or three years," shopper Ryan Jackson said. "And then the same year, the real big-ticket item part is the experience. We want to have more experiences with them, more than, things that are there.” So store owners and the mall are feeling positive heading into the holidays. “We see a direct correlation between how the stock market performs as to how sales perform here at the mall," Kauffman said. "You know, it's been a pretty good run for the stock market. And it's been a pretty good run for us."
Waterdrop Credit stands as a trusted ally in the fight against identity theft and credit fraud, providing valuable insights and guidance to individuals facing such challenges. By empowering individuals with the tools and knowledge to protect their financial security, Waterdrop Credit aims to create a safer and more secure environment for all consumers.
The jokes are writing themselves with the New England Patriots right now. New England announced on Tuesday that they have released guard Michael Jordan. The move is to make room for fellow guard Lester Cotton , whom the Patriots just claimed off waivers from the Miami Dolphins . Naturally, the roster move led to some great jokes on social media. Many X users started referencing the (slightly more popular) guard Michael Jordan of basketball fame. This is why LeBron is the GOAT — JaguarGator9 (@JaguarGator9NFL) November 26, 2024 For the football-playing Jordan to be released is actually somewhat of a surprise. The former fourth-round pick had started 11 of 12 games for the Patriots at left guard this season while Cotton still has yet to make a single start in 2024. But the 3-9 Patriots have decided to make a change regardless. That means these will be the last Air Jordan jokes in New England for a while to come (though there have been plenty of other jokes to get off about the Patriots this season ). This article first appeared on Larry Brown Sports and was syndicated with permission.‘Doesn’t come across great’ – talkSPORT pundits clash as Jude Bellingham reveals the truth about Euro 2024 media scrutiny
In 2024, city moved ahead with Metro; IIT-K shone with record placements & innovations
The jokes are writing themselves with the New England Patriots right now. New England announced on Tuesday that they have released guard Michael Jordan. The move is to make room for fellow guard Lester Cotton , whom the Patriots just claimed off waivers from the Miami Dolphins . Naturally, the roster move led to some great jokes on social media. Many X users started referencing the (slightly more popular) guard Michael Jordan of basketball fame. This is why LeBron is the GOAT — JaguarGator9 (@JaguarGator9NFL) November 26, 2024 For the football-playing Jordan to be released is actually somewhat of a surprise. The former fourth-round pick had started 11 of 12 games for the Patriots at left guard this season while Cotton still has yet to make a single start in 2024. But the 3-9 Patriots have decided to make a change regardless. That means these will be the last Air Jordan jokes in New England for a while to come (though there have been plenty of other jokes to get off about the Patriots this season ). This article first appeared on Larry Brown Sports and was syndicated with permission.DAYTONA BEACH, Fla. (AP) — Ian Schieffelin had 18 points, 13 rebounds and eight assists in leading Clemson to a 75-67 win over Penn State on Tuesday and the championship of the Sunshine Slam Beach Division. Chase Hunter added 17 points, Chauncey Wiggins 14 and Del Jones 10 for the Tigers (6-1), who shot 44% and made 9 of 19 3-pointers led by Hunter's three. Javascript is required for you to be able to read premium content. Please enable it in your browser settings.Scanlan: Time for legislators to protect womenAlabama flips RB Jace Clarizio from Michigan State
Moreover, TSMC's strong sales performance in November serves as a testament to the resilience and adaptability of the company in a rapidly changing economic landscape. Despite the challenges posed by the global supply chain disruptions and fluctuations in market demand, TSMC has demonstrated its ability to navigate through uncertainties and deliver robust financial results.Man City stumble again while Arsenal and Bayern Munich earn dominant wins
The international community has been closely monitoring the developments surrounding the case of Yoo Byung-eun, with many countries expressing support for South Korea's efforts to bring him to justice. The resolution passed by the National Assembly has further amplified the global spotlight on the issue, underscoring the importance of holding individuals accountable for their role in tragedies of this magnitude.Repealing no-fault divorce has so far stalled across the US. Some worry that’ll change under Trump
50 EH/s expansion accelerated to H1 2025 Focused on alternative funding instruments Potential for investor distributions in 2025 Transition to U.S. domestic issuer SYDNEY, Nov. 26, 2024 (GLOBE NEWSWIRE) -- IREN (NASDAQ: IREN ) (together with its subsidiaries, "IREN” or "the Company”), today reported its financial results for the first quarter ended September 30, 2024. All $ amounts are in United States Dollars ("USD”) unless otherwise stated. "We are pleased to report our Q1 FY25 results and reiterate our focus on low-cost Bitcoin mining, operating cashflows and shareholder returns,” said Daniel Roberts, Co-Founder and Co-CEO of IREN. "We are just weeks away from achieving our 31 EH/s milestone and are excited to announce the acceleration of our growth trajectory to 50 EH/s in H1 2025, which was previously H2 2025. Our funding program is focused on alternative funding instruments and the strong operating cashflows we expect to generate enhances our flexibility to support potential distributions in 2025.” Business Update Bitcoin Mining (USD$m) 1 Sep 30, 2024 June 30, 2024 (USD$m) Sep 30, 2024 June 30, 2024 This press release includes "forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements generally relate to future events or IREN's future financial or operating performance. For example, forward-looking statements include but are not limited to the Company's business strategy, expected operational and financial results, and expected increase in power capacity and hashrate. In some cases, you can identify forward-looking statements by terminology such as "anticipate,” "believe,” "may,” "can,” "should,” "could,” "might,” "plan,” "possible,” "project,” "strive,” "budget,” "forecast,” "expect,” "intend,” "target”, "will,” "estimate,” "predict,” "potential,” "continue,” "scheduled” or the negatives of these terms or variations of them or similar terminology, but the absence of these words does not mean that statement is not forward-looking. Such forward-looking statements are subject to risks, uncertainties, and other factors which could cause actual results to differ materially from those expressed or implied by such forward-looking statements. In addition, any statements or information that refer to expectations, beliefs, plans, projections, objectives, performance or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking. These forward-looking statements are based on management's current expectations and beliefs. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause IREN's actual results, performance or achievements to be materially different from any future results performance or achievements expressed or implied by the forward looking statements, including, but not limited to: Bitcoin price and foreign currency exchange rate fluctuations; IREN's ability to obtain additional capital on commercially reasonable terms and in a timely manner to meet its capital needs and facilitate its expansion plans; the terms of any future financing or any refinancing, restructuring or modification to the terms of any future financing, which could require IREN to comply with onerous covenants or restrictions, and its ability to service its debt obligations, any of which could restrict its business operations and adversely impact its financial condition, cash flows and results of operations; IREN's ability to successfully execute on its growth strategies and operating plans, including its ability to continue to develop its existing data center sites and to diversify and expand into the market for high performance computing ("HPC”) solutions it may offer (including the market for AI Cloud Services); IREN's limited experience with respect to new markets it has entered or may seek to enter, including the market for HPC solutions (including AI Cloud Services); expectations with respect to the ongoing profitability, viability, operability, security, popularity and public perceptions of the Bitcoin network; expectations with respect to the profitability, viability, operability, security, popularity and public perceptions of any current and future HPC solutions (including AI Cloud Services) that IREN offers; IREN's ability to secure and retain customers on commercially reasonable terms or at all, particularly as it relates to its strategy to expand into markets for HPC solutions (including AI Cloud Services); IREN's ability to manage counterparty risk (including credit risk) associated with any current or future customers, including customers of its HPC solutions (including AI Cloud Services) and other counterparties; the risk that any current or future customers, including customers of its HPC solutions (including AI Cloud Services), or other counterparties may terminate, default on or underperform their contractual obligations; Bitcoin global hashrate fluctuations; IREN's ability to secure renewable energy, renewable energy certificates, power capacity, facilities and sites on commercially reasonable terms or at all; delays associated with, or failure to obtain or complete, permitting approvals, grid connections and other development activities customary for greenfield or brownfield infrastructure projects; IREN's reliance on power and utilities providers, third party mining pools, exchanges, banks, insurance providers and its ability to maintain relationships with such parties; expectations regarding availability and pricing of electricity; IREN's participation and ability to successfully participate in demand response products and services and other load management programs run, operated or offered by electricity network operators, regulators or electricity market operators; the availability, reliability and/or cost of electricity supply, hardware and electrical and data center infrastructure, including with respect to any electricity outages and any laws and regulations that may restrict the electricity supply available to IREN; any variance between the actual operating performance of IREN's miner hardware achieved compared to the nameplate performance including hashrate; IREN's ability to curtail its electricity consumption and/or monetize electricity depending on market conditions, including changes in Bitcoin mining economics and prevailing electricity prices; actions undertaken by electricity network and market operators, regulators, governments or communities in the regions in which IREN operates; the availability, suitability, reliability and cost of internet connections at IREN's facilities; IREN's ability to secure additional hardware, including hardware for Bitcoin mining and any current or future HPC solutions (including AI Cloud Services) it offers, on commercially reasonable terms or at all, and any delays or reductions in the supply of such hardware or increases in the cost of procuring such hardware; expectations with respect to the useful life and obsolescence of hardware (including hardware for Bitcoin mining as well as hardware for other applications, including any current or future HPC solutions (including AI Cloud Services) IREN offers); delays, increases in costs or reductions in the supply of equipment used in IREN's operations; IREN's ability to operate in an evolving regulatory environment; IREN's ability to successfully operate and maintain its property and infrastructure; reliability and performance of IREN's infrastructure compared to expectations; malicious attacks on IREN's property, infrastructure or IT systems; IREN's ability to maintain in good standing the operating and other permits and licenses required for its operations and business; IREN's ability to obtain, maintain, protect and enforce its intellectual property rights and confidential information; any intellectual property infringement and product liability claims; whether the secular trends IREN expects to drive growth in its business materialize to the degree it expects them to, or at all; any pending or future acquisitions, dispositions, joint ventures or other strategic transactions; the occurrence of any environmental, health and safety incidents at IREN's sites, and any material costs relating to environmental, health and safety requirements or liabilities; damage to IREN's property and infrastructure and the risk that any insurance IREN maintains may not fully cover all potential exposures; ongoing proceedings relating in part to the default, and any future litigation, claims and/or regulatory investigations, and the costs, expenses, use of resources, diversion of management time and efforts, liability and damages that may result therefrom; IREN's failure to comply with any laws including the anti-corruption laws of the United States and various international jurisdictions; any failure of IREN's compliance and risk management methods; any laws, regulations and ethical standards that may relate to IREN's business, including those that relate to Bitcoin and the Bitcoin mining industry and those that relate to any other services it offers, including laws and regulations related to data privacy, cybersecurity and the storage, use or processing of information and consumer laws; IREN's ability to attract, motivate and retain senior management and qualified employees; increased risks to IREN's global operations including, but not limited to, political instability, acts of terrorism, theft and vandalism, cyberattacks and other cybersecurity incidents and unexpected regulatory and economic sanctions changes, among other things; climate change, severe weather conditions and natural and man-made disasters that may materially adversely affect IREN's business, financial condition and results of operations; public health crises, including an outbreak of an infectious disease (such as COVID-19) and any governmental or industry measures taken in response; IREN's ability to remain competitive in dynamic and rapidly evolving industries; damage to IREN's brand and reputation; expectations relating to Environmental, Social or Governance issues or reporting; the costs of being a public company; the increased regulatory and compliance costs of IREN ceasing to be a foreign private issuer and an emerging growth company, as a result of which we will be required, among other things, to file periodic reports and registration statements on U.S. domestic issuer forms with the SEC commencing with our next fiscal year, prepare our financial statements in accordance with U.S. GAAP rather than IFRS, and to modify certain of our policies to comply with corporate governance practices required of U.S. domestic issuers; and other important factors discussed under the caption "Risk Factors” in IREN's annual report on Form 20-F filed with the SEC on August 28, 2024 as such factors may be updated from time to time in its other filings with the SEC, accessible on the SEC's website at www.sec.gov and the Investor Relations section of IREN's website at https://investors.iren.com. These and other important factors could cause actual results to differ materially from those indicated by the forward-looking statements made in this investor update. Any forward-looking statement that IREN makes in this investor update speaks only as of the date of such statement. Except as required by law, IREN disclaims any obligation to update or revise, or to publicly announce any update or revision to, any of the forward-looking statements, whether as a result of new information, future events or otherwise. Non-IFRS Financial Measures This press release includes non-IFRS financial measures, including Net electricity costs, Adjusted EBITDA and Adjusted EBITDA Margin. We provide these measures in addition to, and not as a substitute for, measures of financial performance prepared in accordance with IFRS. There are a number of limitations related to the use of Net electricity costs, Adjusted EBTIDA and Adjusted EBITDA Margin. For example, other companies, including companies in our industry, may calculate these measures differently. The Company believes that these measures are important and supplement discussions and analysis of its results of operations and enhances an understanding of its operating performance. EBITDA is calculated as our IFRS profit/(loss) after income tax expense, excluding interest income, finance expense and non-cash fair value loss and interest expense on hybrid financial instruments, income tax expense, depreciation and amortization, which are important components of our IFRS profit/(loss) after income tax expense. Further, "Adjusted EBITDA” also excludes share-based payments expense, which is an important component of our IFRS profit/(loss) after income tax expense, foreign exchange gains and losses, impairment of assets, certain other non-recurring income, loss on disposal of property, plant and equipment, gain on disposal of subsidiaries, unrealized fair value gains and losses on financial assets and certain other expense items. Net electricity costs is calculated as our IFRS Electricity charges net of Realized gain/(loss) on financial asset, ERS revenue (included in Other income) and ERS fees (included in Other operating expenses), and excludes the cost of Renewable Energy Certificates (RECs). About IREN IREN is a leading data center business powering the future of Bitcoin, AI and beyond utilizing 100% renewable energy. Sodali & Co +61 477 946 068 IREN +61 407 423 395 [email protected] Aircover Communications +1 510 333 2707
As the investigation unfolds, the eyes of the football world are on Milan, waiting to see how the situation will develop and what outcomes will arise. The case serves as a reminder of the importance of maintaining trust and accountability in football, as well as the need for clubs to conduct themselves ethically and responsibly to safeguard the integrity of the sport.Furthermore, Xiaomi's relentless focus on customer satisfaction and experience has been instrumental in fueling its sales growth. By providing top-notch service and support to customers, Xiaomi has built a loyal fan base that continues to drive sales through word-of-mouth referrals and positive reviews. This customer-centric approach has proven to be a winning strategy for Xiaomi, as it continues to outperform expectations in the highly competitive automotive market.
Published 4:48 pm Tuesday, November 26, 2024 By Data Skrive The Duke Blue Devils and the Oklahoma Sooners take the court in one of six games on the college basketball slate on Wednesday that include a ranked team. Watch women’s college basketball, other live sports and more on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Use our link to sign up for a free trial. Catch tons of live women’s college basketball , plus original programming, with ESPN+ or the Disney Bundle.Lewandowski joins Ronaldo and Messi in Champions League 100-goal club. Haaland nets 2 but City draws
Sporting Lisbon fans cause chaos with fireworks during Arsenal clash in Champions League - as they explode over David Raya's penalty area
- Previous:
- Next: fish 2 go franchise