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After Trump’s win, Black women are rethinking their role as America’s reliable political organizersWARSAW, Ind. , Nov. 25, 2024 /PRNewswire/ -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), a global medical technology leader, today announced U.S. Food and Drug Administration (FDA) Premarket Approval Application (PMA) Supplement approval for the Oxford ® Cementless Partial Knee. The approval is based on safety and effectiveness data from an Investigational Device Exemption (IDE) study and non-clinical testing for cementless partial knee replacement (PKR). 1 The Oxford Cementless Partial Knee allows surgeons to perform a PKR with improved fixation, 2 better long-term implant survival rate 2,3 and improved efficiency in the operating room 4 (OR) compared to the Oxford Cemented Partial Knee procedure. Following more than 20 years of clinical experience and over 300,000 procedures across Canada , Europe , Middle East , Africa , and Asia , 5 the Oxford Cementless Partial Knee is now the only FDA-approved cementless partial knee implant in the U.S. "Cementless knee replacement procedures are increasingly preferred by surgeons seeking to improve surgical efficiency. The Oxford Cementless Partial Knee is coming into the U.S. with a proven track record of retaining more healthy anatomy with a less invasive approach and improved outcomes 6 as compared to a total knee replacement," said Joe Urban , President, Knees at Zimmer Biomet. "We are excited to address the unmet U.S. demand for a cementless partial knee with a new offering which has 20 years of clinical experience in more than 50 countries. 5 " Compared to traditional partial knee replacements that use bone cement to secure the implant in place, a cementless approach allows patients' natural bone growth to secure the implant for better long-term fixation. 2 The Oxford Cementless Partial Knee features a mobile bearing that can move with the femoral component throughout the entire range of motion to mimic natural knee movement. This design provides better range of motion, a more natural feel and a more stable implant-to-bone fixation for improved long-term implant survival. 2,3 The system's tibial and femoral components have a titanium and hydroxyapatite coating to promote bone growth into the implant 7 . The UK national joint registry has more than 33,000 patients treated with Oxford Cementless Partial Knees recorded with a 94.1% rate of implant survival at 10 years after surgery, 3 which is higher than the average 10-year survivorship for all other partial knees (89.9%). 3 Enthusiasm and usage of partial knee replacement continues to grow around the world as published research continues to demonstrate that PKR in appropriate cases provides improved patient outcomes compared to TKR. 6 "For younger and more active patients, the Oxford Cementless Partial Knee amplifies the benefits of a traditional partial knee replacement by offering knee flexion that resembles natural knee movement, and stronger adhesion of the implant to the bone for better long-term durability," said Adolph V. Lombardi Jr. , MD, FACS, President of JIS Orthopedics in New Albany, Ohio . "In my own practice, a cementless approach has increased OR efficiency by shortening my surgery time and reducing costs associated with cement preparation." Since its initial launch in England in 2004, the Oxford Cementless Partial Knee has become the preferred partial knee implant for Zimmer Biomet's European customers. 5 As part of the U.S. nationwide launch in Q1 2025, Zimmer Biomet will provide FDA-required training, focusing on the cementless surgical technique and proper patient selection. For patients in the U.S., the Oxford Partial Knee is the only implant with a lifetime limited warranty that covers the cost of Zimmer Biomet replacement implants.* Important Safety Information: The Cementless Oxford Partial Knee System is intended for use in unilateral knee procedures with osteoarthritis or avascular necrosis limited to the medial compartment of the knee. It is intended to be implanted without the application of cement for patients whose clinical condition would benefit from a shorter surgical time compared to the cemented implant. The Oxford Partial Knee is not indicated for use in the lateral compartment or for patients with ligament deficiency, or for use in simultaneous bilateral surgery or planned staged bilateral procedures. Potential risks include, but are not limited to, loosening, dislocation, fracture, wear and infection, any of which can require additional surgery. For a full list of product indications, contraindications and warnings, as well as further information on product IDE data, please see the associated product Information for Use (IFU) and Surgical Technique available at https://labeling.zimmerbiomet.com/ For more information about the Oxford Cementless Partial Knee, visit www.zimmerbiomet.com/oxfordcementless . About Zimmer Biomet Zimmer Biomet is a global medical technology leader with a comprehensive portfolio designed to maximize mobility and improve health. We seamlessly transform the patient experience through our innovative products and suite of integrated digital and robotic technologies that leverage data, data analytics and artificial intelligence. With 90+ years of trusted leadership and proven expertise, Zimmer Biomet is positioned to deliver the highest quality solutions to patients and providers. Our legacy continues to come to life today through our progressive culture of evolution and innovation. For more information about our product portfolio, our operations in 25+ countries and sales in 100+ countries or about joining our team, visit www.zimmerbiomet.com or follow on LinkedIn at www.linkedin.com/company/zimmerbiomet or X / Twitter at www.twitter.com/zimmerbiomet . Cautionary Statement Regarding Forward-Looking Statements This news release contains forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include, but are not limited to, statements concerning Zimmer Biomet's expectations, plans, prospects, and product and service offerings, including new product launches and potential clinical successes. Such statements are based upon the current beliefs and expectations of management and are subject to significant risks, uncertainties and changes in circumstances that could cause actual outcomes and results to differ materially. For a list and description of some of such risks and uncertainties, see Zimmer Biomet's periodic reports filed with the U.S. Securities and Exchange Commission (SEC). These factors should not be construed as exhaustive and should be read in conjunction with the other cautionary statements that are included in Zimmer Biomet's filings with the SEC. Forward-looking statements speak only as of the date they are made, and Zimmer Biomet disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. Readers of this news release are cautioned not to rely on these forward-looking statements, since there can be no assurance that these forward-looking statements will prove to be accurate. This cautionary statement is applicable to all forward-looking statements contained in this news release. *Subject to terms and conditions set forth within the written warranty References: Media Heather Zoumas-Lubeski 445-248-0577 heather.zoumaslubeski@zimmerbiomet.com Kirsten Fallon 781-779-5561 kirsten.fallon@zimmerbiomet.com Investors David DeMartino 646-531-6115 david.demartino@zimmerbiomet.com Zach Weiner 908-591-6955 Zach.weiner@zimmerbiomet.com View original content to download multimedia: https://www.prnewswire.com/news-releases/zimmer-biomet-receives-fda-approval-for-oxford-cementless-partial-knee-only-cementless-partial-knee-replacement-implant-in-the-us-302315755.html SOURCE Zimmer Biomet Holdings, Inc.

Finding the can be daunting. The only way to truly ensure you get it right would be to ask the recipient what they want, but that wouldn’t be much fun for either of you. Luckily, there’s another tactic to help you earn a “gift whisperer” reputation: seeking out unique, practical, game-changing gifts that will truly surprise and delight. But that’s about as easy as it sounds, which is to say it’s not easy at all. So, we’ve done the legwork for you. Start making your list with this compilation of some of the most innovative, functional and fun gifts of 2024. There’s something for every budget. Bear with me: The new set elevates the pedestrian pepper and spice mill in both function and style. Available in three colors (Sangria Red, Midnight Black and Soft Cream), the rechargeable-battery unit grinds with a light touch rather than hand-tiring twists. That’s easier for everyone and especially helpful for those experiencing hand or wrist issues such as arthritis, carpal tunnel syndrome or tendinitis. And it’s fun to use. The set includes a stackable storage tray and four pods that can be easily swapped as needed: The GT microplane grater for hard spices, nuts and chocolate; the MAX for large spices and dried herbs; the ProPlus for smaller and oily spices; and the Pepper Pod for, well, pepper. $110. Campers and backyard firepit lovers who have experienced the heartbreak of wet wood will appreciate having a three-pack of on hand. Made of 89% recycled materials, including sanding dust, wax and flint, the food-safe, eco-friendly, 3-by-2-by-1-inch fire starters will light a fire quickly without matches, lighters or kindling. Just loop the attached green string around a log, incorporate it into a wood stack, and pull the attached red string to ignite. Each windproof, rainproof block burns for 30 minutes. $29.99. The , a company known for its portioned, silicone freezer trays, lives up to its name. The utensils — a serving spoon and a ladle — have innovative, S-shaped handles designed to rest on the edge of a pot, keeping them upright so they won’t slip in. The design also eliminates the need for a spoon rest or, worse, placing dirty utensils on the kitchen counter or stovetop between stirs. A silicone coating in a choice of Aqua, Charcoal, Cranberry or Blueberry keeps handles cool to the touch. $24.99. The could turn anyone into an avid birdwatcher. Equipped with an HD camera, the dual-chamber feeder enables up-close livestreaming of avian visitors, as well as species-logging via the free mobile app. An optional premium subscription ($59.99 annually or $6.99 monthly) includes unlimited photo and video storage, AI identification with species-specific details, and the opportunity to earn badges for logging new visitors. Turn on notifications to get alerts sent to your phone whenever there’s activity at the feeder. $179.99. Fujifilm’s smartphone printer offers a touch of nostalgia without sacrificing technology. Just load the 4.9-by-3.5-by-1.3-inch printer with Instax Mini instant film and connect it to your Android or iOS device via Bluetooth to print wallet-size photos. If you want to get fancy, you can adjust brightness, contrast and saturation, or apply filters, including 3D augmented-reality effects, via the free Instax Mini Link app. It can also make collages of up to six images, or animate photos to share on social media. Available in Rose Pink, Clay White and Sage Green. $99.95. The appropriately named is one of the best gifts you can give your houseplant-loving friends, regardless of their experience level. Select a pot color, size and plant (or get recommendations based on sunlight requirements, pet friendliness and other attributes) and fill the self-watering container’s built-in reservoir roughly once a month. Moisture will permeate the soil from the bottom as needed, eliminating the often-fatal consequences of over- or under-watering. It’s also a literal lifesaver come vacation time. $49-$259. If you’ve got a no-dairy friend on your list, a plant-based milk maker could save them money while allowing them to avoid sugar, stabilizers, thickeners and preservatives. The both blends and strains ingredients, converting nuts, seeds, grains or oats into velvety-smooth milk in just one minute, with zero grit. And for zero waste, the pasty leftover pulp can be used in other recipes for added nutrients. The device also makes infused oils, flavored waters and soups. And, importantly, cleanup is easy. Available in white and black. $400. For friends who prefer stronger beverages, the uses “smart” technology to ensure wine is served at its ideal temperature. Unlike traditional wine refrigerators, this device doesn’t take up any floor space. It also doesn’t chill wine to just one or two temperatures based on its color. Instead — paired with the free QelviQ app — the tabletop chiller relies on a database of more than 350,000 wines to bring a bottle to its specific recommended serving temperature in as little as 20 minutes. It also suggests food-wine and wine-food pairings. Plus, the appliance serves as a great icebreaker to inspire dinnertime conversation. Available in Exciting Red, Dashing Black and Dreamy White. $495. Grilling food after dark — and ascertaining its doneness — can prove challenging without outdoor lighting, and it’s nearly impossible to cook while holding a flashlight. But as is often the case, the simplest of solutions can make the biggest of impacts: puts illumination into the handles of its stainless-steel spatula and tongs. After use, the lights can be removed and the utensils run through the dishwasher. $40.SHAREHOLDER INVESTIGATION: Halper Sadeh LLC Investigates AE, ENLC, SKGR, EVGR on Behalf of ShareholdersThe Secret to a Winning Smile? Award-Winning Dentist Dr. Curry

Mexican President Claudia Sheinbaum responded to U.S. President-elect Donald Trump in a letter published Tuesday, addressing the issue of the fentanyl crisis and broader drug-related challenges. Her message emphasized cooperation over confrontation — whereas Trump has a penchant for the latter . “Neither threats nor tariffs will solve the migration or the drug abuse phenomenon in the US,” Sheinbaum said , calling for collaborative solutions to mitigate the escalating drug crisis. Migración y consumo de fentanilo no se atenderán con amenazas ni aranceles. México avanza con resultados en acciones integrales; la cooperación y el entendimiento son necesarios. El diálogo es el camino. pic.twitter.com/mwXkhUCwbL Sheinbaum To Trump: Fentanyl ‘Is An Issue In Your Country’ “For humanitarian reasons, we have consistently expressed Mexico’s commitment to preventing the continuation of the fentanyl epidemic in the United States, which, moreover, is an issue of consumption and public health in your country,” Sheinbaum says in the letter, which she read during her usual morning conferences. Sheinbaum detailed Mexico's recent measures, including enforcement actions by the armed forces and prosecutors. According to the data she shared, in 2024 alone, authorities seized large quantities of “various drugs”, confiscated over 10,340 firearms, and arrested more than 15,640 individuals for drug-related violence. Furthermore, she noted Mexico’s legislative progress toward stricter penalties. Get Benzinga’s exclusive analysis and the top news about the cannabis industry and markets daily in your inbox for free. Subscribe to our newsletter here . If you’re serious about the business, you can’t afford to miss out. Not Us Sheinbaum called attention to the illicit flow of chemical precursors from Asia, which enter North America through Canada, the U.S., and Mexico. She stressed that addressing this issue requires international collaboration: “It is publicly known that these precursors are smuggled into North America. This makes global cooperation imperative.” The president juxtaposed the flow of drugs with the southbound illegal trafficking of firearms from the U.S. into Mexico . She cited stark statistics: 70% of illegal weapons seized in Mexico originate in the U.S., fueling violence. “The synthetic drugs are not consumed by us, and the weapons are not produced here. Yet, we bear the brunt of the deaths caused by organized crime in response to the demand for drugs in your country.” Read Also: How Trump’s Election Could Revolutionize Cannabis And Cryptocurrency, CEO Says ‘Reciprocal Understanding And Cooperation’ Sheinbaum rejected the efficacy of punitive tariffs in addressing these challenges. Instead, she urged for “reciprocal understanding and cooperation” between the two nations. She noted that mutual economic ties, especially in industries like automotive manufacturing, would suffer under an antagonistic approach, leading to inflation and job losses on both sides of the border, and posed that both Mexico and the U.S. should work together on a mobility program instead of reinforcing the borders. “I am convinced that North America's economic strength lies in preserving our commercial partnership. Dialogue is the best path toward understanding, peace, and prosperity for our nations,” she added. Read Next: Goldman Sachs Expects Major Selloffs In Canadian Dollar, Mexican Peso, Says Trump Tariffs Threaten USMCA Agreement Translations in this article were made by Rolando García Cover: Shutterstock . © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.WEC Energy director Gale Klappa sells $4.4m in stockKey details to know about the arrest of a suspect in the killing of UnitedHealthcare's CEO